Behcet’s disease is a rare disease with painful mouth and genital ulcers, along with eye, skin and other problems. The cause is thought to be immune. This is rare in the UK but occurs in about 1 in 10 000 people living in the Mediterranean basin, Middle and Far East.
Mouth ulcers are the most common sign of Behcet disease. The other common signs are ulcers on the genitalia, eye changes, lumps on the shins and acne type spots. Sore throats, loss of weight, aches and pains, fatigue, headache and a feeling of hot or cold, can occur.
Less commonly, arthritis, gastrointestinal (e.g. abdominal pain, diarrhoea, vomiting), nervous system and circulation problems can occur. It can be difficult to diagnose as symptoms come and go.